Ian Wanless

Patologia Hepática, Trato Biliar e Pâncreas Exócrino Canadá

Dr. Ian R. Wanless, MD, FRCPC, FAASLD

Staff Pathologist, Department of Pathology,

Dalhousie University, Halifax, Canada

Dr. Wanless is a graduate of McGill University, with post-graduate training at the University of Alberta and Cornell University Medical College. After spending 28 years at the University of Toronto, he is now a Professor of Pathology at Dalhousie University and Queen Elizabeth II Health Sciences Centre in Halifax.

Dr.Wanless’ research has concentrated on 3 areas of liver pathology, including steatohepatitis, nodular hyperplasia, and the role of vascular events in the pathogenesis and regression of cirrhosis, as well as other lesions.

His studies were the first to document the role of insulin and hyperinsulinemia in human fatty liver disease, providing insight into the pathogenesis of fatty liver occurring in obesity (NASH), alcoholism, and post-jejuno-ileal bypass. He demonstrated how heterogeneity of insulin delivery to the tissues explains focal fatty change and focal fatty sparing.

His studies of the hepatic vasculature provide insights for the pathogenesis of focal nodular hyperplasia, nodular regenerative hyperplasia, non-cirrhotic portal hypertension, and cirrhosis. Current work is concentrated on the importance of parenchymal extinction in the development of cirrhosis and how this affects the interpretation of fibrosis in the liver.

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